HUBUNGAN PENGGUNAAN NARKOTIKA SUNTIK DENGAN KOINFEKSI HEPATITIS C DI RSUD TEBET TAHUN 2017-2019
Abstract
Background: The number of people who was infected HIV/AIDS over the world approximately 37,9 milion in 2018. Hepatitis C coinfection in HIV patients approximately 2-15% over the world and for 90% were injecting drug users. This study aims to find the correlation injecting drug use and hepatitis C coinfection in HIV patients in RSUD Tebet from 2017-2019. Method: This study use case-control design using medical record data. We studied 186 samples and use simple random sampling for recruiting sample. Analysis of the data used SPSS software and were analyzed by univarit, bibariat, multivariat with logistic regression. Results: Injecting drug use showed a significant correlation with Hepatitis C coinfection in HIV patients with OR adjusted 12,7 (95% CI (3,8 - 42,37) and p-value 0,001 after adjusted with working status, age, sex, and risky sexual behavior. Conclution: Injecting drug use showed a significant correlation with Hepatitis C coinfection in RSUD Tebet.
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References
Greub G, Ledergerber B, Battegay M, Grob P, Perrin L, Furrer H, et al. Clinical progression, survival, and immune recovery during antiretroviral therapy in patients with HIV-1 and hepatitis C virus coinfection: The swiss HIV cohort study. Lancet. 2000;356(9244):1800–5.
Kemenkes RI. Laporan Nasional Riskesdas Tahun 2018. Jakarta;
Kurniawati SA, Karjadi TH, Gani RA. Faktor - Faktor yang Berhubungan dengan Kejadian Hepatitis C pada Pasangan Seksual Pasien Koinfeksi Human Immunodeficiency Virus dan Virus Hepatitis C. 2015;2(3):133–9.
Operskalski EA, Kovacs A. HIV / HCV Co-infection : Pathogenesis , Clinical Complications ,
Province Y, Zhou Y, Yao Z, Liu F, Li H, Jiang L, et al. High Prevalence of HIV , HCV , HBV and Co-Infection and Associated Risk Factors among Injecting Drug Users in. 2012;7(8).
Tian KL, Wu JX, Suo J, Yang ZH LJ. Study on blood-borne virus co- infection and T lymphocyte subset in intravenous drug users. Chin J Public Heal. 2009;25:742–744
Sulkowski MS, Mast EE, Seeff LB, Thomas DL. Hepatitis C Virus Infection as an Opportunistic Disease in Persons Infected with Human Immunodeficiency Virus. :77–84.
Villano SA, Vlahov D, Nelson KE, Lyles CM, Cohn S, Thomas DL. Incidence and risk factors for hepatitis C among injection drug users in Baltimore, Maryland. J Clin Microbiol. 1997;35(12):3274–7.
WHO. Global hepatitis report, 2017,Geneva 2017.
WHO. Progress report on HIV, viral hepatitis and sexually transmitted infections, 2019. Geneva; 2019.
